:root {
  /* Brand Colors */
  --navy-deep: #001E44;
  --blue-primary: #1E407C;
  --blue-light: #96BEE6;
  --white-base: #FFFFFF;

  /* Derived palette */
  --navy: var(--navy-deep);
  --navy-light: #0A2A54;
  --blue-mid: var(--blue-primary);
  --accent: var(--blue-light);
  --accent-dim: rgba(150, 190, 230, 0.15);
  --accent-bright: #B8D4F0;
  --white: var(--white-base);
  --gray-50: #F5F7FA;
  --gray-100: #EBF0F5;
  --gray-200: #D4DCE6;
  --gray-400: #7A8799;
  --gray-600: #3D4A5C;
  --gray-800: #1A2538;

  --font-display: 'Fraunces', Georgia, serif;
  --font-body: 'Outfit', system-ui, sans-serif;
  --font-mono: 'Space Mono', monospace;

  --space-xs: 0.5rem;
  --space-sm: 1rem;
  --space-md: 1.5rem;
  --space-lg: 3rem;
  --space-xl: 5rem;
  --space-2xl: 8rem;

  --max-w: 1120px;
  --radius: 6px;
}

*,
*::before,
*::after {
  margin: 0;
  padding: 0;
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
  -webkit-text-size-adjust: 100%;
}

body {
  font-family: var(--font-body);
  font-weight: 400;
  font-size: 1rem;
  line-height: 1.65;
  color: var(--gray-800);
  background: var(--white);
  -webkit-font-smoothing: antialiased;
}

::selection {
  background: var(--accent);
  color: var(--navy);
}

a {
  color: inherit;
  text-decoration: none;
}

img {
  display: block;
  max-width: 100%;
}

/* ---- NAV ---- */

.nav {
  position: fixed;
  top: 0;
  left: 0;
  right: 0;
  z-index: 100;
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: 0 var(--space-md);
  height: 60px;
  background: rgba(0, 30, 68, 0.94);
  backdrop-filter: blur(12px);
  -webkit-backdrop-filter: blur(12px);
  border-bottom: 1px solid rgba(255, 255, 255, 0.06);
}

.nav-logo {
  display: flex;
  align-items: center;
  gap: 0.6rem;
  color: var(--white);
  font-family: var(--font-display);
  font-weight: 500;
  font-size: 1.05rem;
  letter-spacing: -0.01em;
}

.nav-logo-icon {
  color: var(--blue-light);
}

.nav-links {
  display: flex;
  align-items: center;
  gap: 2rem;
}

.nav-links a {
  color: var(--gray-400);
  font-size: 0.85rem;
  font-weight: 500;
  letter-spacing: 0.02em;
  transition: color 0.2s;
}

.nav-links a:hover,
.nav-links a:focus-visible {
  color: var(--white);
}

.nav-cta {
  padding: 0.4rem 1rem;
  border: 1px solid var(--blue-light);
  border-radius: var(--radius);
  color: var(--blue-light) !important;
  transition: background 0.2s, color 0.2s;
}

.nav-cta:hover {
  background: var(--blue-light);
  color: var(--navy-deep) !important;
}

.nav-toggle {
  display: none;
  background: none;
  border: none;
  cursor: pointer;
  width: 28px;
  height: 20px;
  position: relative;
}

.nav-toggle span {
  display: block;
  width: 100%;
  height: 2px;
  background: var(--white);
  border-radius: 1px;
  position: absolute;
  left: 0;
  transition: transform 0.3s, opacity 0.3s;
}

.nav-toggle span:first-child { top: 4px; }
.nav-toggle span:last-child { bottom: 4px; }

/* ---- HERO ---- */

.hero {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: var(--space-lg);
  align-items: center;
  min-height: 100vh;
  padding: calc(60px + var(--space-xl)) var(--space-md) var(--space-xl);
  max-width: var(--max-w);
  margin: 0 auto;
}

.hero-eyebrow {
  font-family: var(--font-mono);
  font-size: 0.75rem;
  letter-spacing: 0.08em;
  text-transform: uppercase;
  color: var(--blue-primary);
  margin-bottom: var(--space-sm);
}

.hero-title {
  font-family: var(--font-display);
  font-size: clamp(2.4rem, 5vw, 3.6rem);
  font-weight: 700;
  line-height: 1.1;
  letter-spacing: -0.025em;
  color: var(--navy);
  margin-bottom: var(--space-md);
}

.hero-title em {
  font-style: italic;
  color: var(--blue-mid);
}

.hero-subtitle {
  font-size: 1.05rem;
  line-height: 1.7;
  color: var(--gray-600);
  max-width: 480px;
  margin-bottom: var(--space-lg);
}

.hero-actions {
  display: flex;
  gap: var(--space-sm);
  flex-wrap: wrap;
}

/* ---- BUTTONS ---- */

.btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  padding: 0.65rem 1.6rem;
  font-family: var(--font-body);
  font-size: 0.9rem;
  font-weight: 500;
  border-radius: var(--radius);
  border: 1.5px solid transparent;
  cursor: pointer;
  transition: all 0.2s;
  text-decoration: none;
}

.btn-primary {
  background: var(--navy);
  color: var(--white);
  border-color: var(--navy);
}

.btn-primary:hover {
  background: var(--blue-primary);
  border-color: var(--blue-primary);
}

.btn-ghost {
  background: transparent;
  color: var(--navy);
  border-color: var(--gray-200);
}

.btn-ghost:hover {
  border-color: var(--navy);
}

.btn-lg {
  padding: 0.85rem 2.2rem;
  font-size: 1rem;
}

/* ---- HERO GENOME VIZ ---- */

.hero-genome {
  display: flex;
  flex-direction: column;
  gap: 10px;
  padding: var(--space-md);
  background: var(--navy);
  border-radius: 8px;
  position: relative;
}

.genome-track {
  display: flex;
  align-items: center;
  gap: 10px;
}

.genome-label {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  color: var(--gray-400);
  width: 36px;
  text-align: right;
  flex-shrink: 0;
}

.genome-bar {
  flex: 1;
  height: 18px;
  display: flex;
  gap: 2px;
  border-radius: 3px;
  overflow: hidden;
  background: rgba(255, 255, 255, 0.04);
}

.genome-segment {
  width: var(--w);
  height: 100%;
  background: var(--c);
  opacity: 0.7;
  border-radius: 2px;
  transition: opacity 0.3s;
}

.genome-segment:hover {
  opacity: 1;
}

.genome-annotation {
  position: relative;
  height: 36px;
  margin-left: 46px;
}

.genome-marker {
  position: absolute;
  left: var(--left);
  top: 0;
  display: flex;
  flex-direction: column;
  align-items: center;
}

.genome-marker-line {
  width: 1px;
  height: 14px;
  background: var(--blue-light);
  opacity: 0.5;
}

.genome-marker-label {
  font-family: var(--font-mono);
  font-size: 0.6rem;
  color: var(--blue-light);
  white-space: nowrap;
  margin-top: 2px;
}

.genome-marker-label sub {
  font-size: 0.5rem;
  opacity: 0.7;
}

/* ---- STATS BAR ---- */

.stats-bar {
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  border-top: 1px solid var(--gray-200);
  border-bottom: 1px solid var(--gray-200);
  max-width: var(--max-w);
  margin: 0 auto;
}

.stat {
  display: flex;
  flex-direction: column;
  align-items: center;
  padding: var(--space-lg) var(--space-sm);
  text-align: center;
}

.stat-value {
  font-family: var(--font-display);
  font-size: 2.2rem;
  font-weight: 300;
  color: var(--navy);
  line-height: 1;
  margin-bottom: 0.4rem;
}

.stat-unit {
  font-size: 1rem;
  color: var(--blue-mid);
}

.stat-label {
  font-size: 0.8rem;
  color: var(--gray-400);
  font-weight: 500;
}

/* ---- SECTIONS ---- */

.section {
  padding: var(--space-2xl) var(--space-md);
  max-width: var(--max-w);
  margin: 0 auto;
}

.section-header {
  max-width: 600px;
  margin-bottom: var(--space-xl);
}

.section-eyebrow {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: var(--blue-primary);
  margin-bottom: var(--space-xs);
}

.section-header h2 {
  font-family: var(--font-display);
  font-size: clamp(1.8rem, 3.5vw, 2.6rem);
  font-weight: 700;
  letter-spacing: -0.02em;
  color: var(--navy);
  line-height: 1.15;
  margin-bottom: var(--space-sm);
}

.section-intro {
  font-size: 1rem;
  color: var(--gray-600);
  line-height: 1.7;
}

/* ---- RESEARCH GRID ---- */

.research-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 1px;
  background: var(--gray-200);
  border: 1px solid var(--gray-200);
  border-radius: 8px;
  overflow: hidden;
}

.research-card {
  background: var(--white);
  padding: var(--space-lg);
  display: flex;
  flex-direction: column;
  transition: background 0.3s;
}

.research-card:hover {
  background: var(--gray-100);
}

.research-card-icon {
  color: var(--blue-mid);
  margin-bottom: var(--space-md);
}

.research-card h3 {
  font-family: var(--font-display);
  font-size: 1.25rem;
  font-weight: 500;
  color: var(--navy);
  margin-bottom: var(--space-xs);
}

.research-card p {
  font-size: 0.88rem;
  color: var(--gray-600);
  line-height: 1.65;
  flex: 1;
}

.research-card-status {
  display: inline-block;
  margin-top: var(--space-md);
  font-family: var(--font-mono);
  font-size: 0.68rem;
  letter-spacing: 0.04em;
  color: var(--blue-primary);
  padding: 0.3rem 0.7rem;
  background: rgba(30, 64, 124, 0.08);
  border-radius: 20px;
  width: fit-content;
}

/* ---- GENOME BROWSER ---- */

.genome-section {
  background: var(--gray-100);
  max-width: none;
  padding-left: var(--space-md);
  padding-right: var(--space-md);
}

.genome-section .section-header,
.genome-section .genome-browser {
  max-width: var(--max-w);
  margin-left: auto;
  margin-right: auto;
}

.genome-browser {
  background: var(--navy);
  border-radius: 8px;
  overflow: hidden;
}

.genome-browser-header {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: var(--space-sm) var(--space-md);
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
  flex-wrap: wrap;
  gap: 0.5rem;
}

.genome-browser-title {
  font-family: var(--font-mono);
  font-size: 0.8rem;
  color: var(--white);
  font-weight: 700;
}

.genome-browser-meta {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  color: var(--gray-400);
}

.genome-browser-body {
  padding: var(--space-md);
  display: flex;
  flex-direction: column;
  gap: 8px;
}

.chromosome-row {
  display: flex;
  align-items: center;
  gap: 12px;
}

.chr-label {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  color: var(--gray-400);
  width: 40px;
  text-align: right;
  flex-shrink: 0;
}

.chr-bar {
  flex: 1;
  height: 14px;
  background: rgba(255, 255, 255, 0.05);
  border-radius: 3px;
  overflow: hidden;
}

.chr-fill {
  height: 100%;
  width: var(--pct);
  background: linear-gradient(90deg, var(--blue-light), var(--blue-primary));
  border-radius: 3px;
  transition: width 1.2s ease-out;
}

.chr-bar-x .chr-fill {
  background: linear-gradient(90deg, var(--blue-light), var(--blue-primary));
}

.chr-pct {
  font-family: var(--font-mono);
  font-size: 0.68rem;
  color: var(--blue-light);
  width: 32px;
  text-align: right;
  flex-shrink: 0;
}

/* ---- DNA BREAK ---- */

.dna-break {
  max-width: none;
  padding: var(--space-md) 0;
  overflow: hidden;
}

.dna-sequence {
  font-family: var(--font-mono);
  font-size: 0.75rem;
  letter-spacing: 0.25em;
  color: var(--gray-200);
  white-space: nowrap;
  animation: scroll-dna 30s linear infinite;
  user-select: none;
}

@keyframes scroll-dna {
  from { transform: translateX(0); }
  to { transform: translateX(-50%); }
}

/* ---- TEAM ---- */

.team-grid {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: var(--space-sm);
}

.team-card {
  display: flex;
  gap: var(--space-sm);
  padding: var(--space-md);
  border: 1px solid var(--gray-200);
  border-radius: var(--radius);
  transition: border-color 0.2s, box-shadow 0.2s;
}

.team-card:hover {
  border-color: var(--gray-400);
  box-shadow: 0 2px 12px rgba(11, 29, 53, 0.06);
}

.team-avatar {
  width: 44px;
  height: 44px;
  border-radius: 50%;
  background: hsl(var(--hue), 35%, 90%);
  color: hsl(var(--hue), 40%, 35%);
  display: flex;
  align-items: center;
  justify-content: center;
  font-family: var(--font-mono);
  font-size: 0.72rem;
  font-weight: 700;
  flex-shrink: 0;
}

.team-info h3 {
  font-family: var(--font-body);
  font-size: 0.95rem;
  font-weight: 600;
  color: var(--navy);
}

.team-role {
  font-family: var(--font-mono);
  font-size: 0.68rem;
  color: var(--blue-primary);
  margin-bottom: 0.3rem;
}

.team-desc {
  font-size: 0.82rem;
  color: var(--gray-600);
  line-height: 1.55;
}

/* ---- PUBLICATIONS ---- */

.pub-list {
  display: flex;
  flex-direction: column;
}

.pub {
  display: grid;
  grid-template-columns: 52px 1fr auto;
  gap: var(--space-md);
  padding: var(--space-md) 0;
  border-bottom: 1px solid var(--gray-200);
  align-items: start;
}

.pub:first-child {
  border-top: 1px solid var(--gray-200);
}

.pub-year {
  font-family: var(--font-mono);
  font-size: 0.75rem;
  color: var(--gray-400);
  padding-top: 0.15rem;
}

.pub-content h3 {
  font-family: var(--font-body);
  font-size: 0.95rem;
  font-weight: 600;
  color: var(--navy);
  line-height: 1.45;
  margin-bottom: 0.3rem;
}

.pub-authors {
  font-size: 0.82rem;
  color: var(--gray-600);
}

.pub-journal {
  font-size: 0.82rem;
  color: var(--gray-400);
}

.pub-tag {
  font-family: var(--font-mono);
  font-size: 0.62rem;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  padding: 0.25rem 0.6rem;
  border-radius: 20px;
  background: rgba(30, 64, 124, 0.08);
  color: var(--blue-primary);
  white-space: nowrap;
  flex-shrink: 0;
  margin-top: 0.15rem;
}

/* ---- JOIN ---- */

.join {
  background: var(--navy);
  max-width: none;
  padding: var(--space-2xl) var(--space-md);
}

.join-content {
  max-width: var(--max-w);
  margin: 0 auto;
}

.join h2 {
  font-family: var(--font-display);
  font-size: clamp(1.8rem, 3.5vw, 2.6rem);
  font-weight: 700;
  color: var(--white);
  letter-spacing: -0.02em;
  margin-bottom: var(--space-sm);
}

.join p {
  color: var(--gray-400);
  max-width: 560px;
  line-height: 1.7;
  margin-bottom: var(--space-lg);
}

.join-details {
  display: flex;
  gap: var(--space-lg);
  margin-bottom: var(--space-lg);
  flex-wrap: wrap;
}

.join-detail {
  display: flex;
  flex-direction: column;
  gap: 0.2rem;
  color: var(--gray-400);
  font-size: 0.9rem;
}

.join-detail-label {
  font-family: var(--font-mono);
  font-size: 0.65rem;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: var(--accent);
}

.join .btn-primary {
  background: var(--accent);
  color: var(--navy);
  border-color: var(--accent);
  font-weight: 600;
}

.join .btn-primary:hover {
  background: var(--accent-bright);
  border-color: var(--accent-bright);
}

/* ---- FOOTER ---- */

.footer {
  border-top: 1px solid var(--gray-200);
  padding: var(--space-lg) var(--space-md);
}

.footer-inner {
  max-width: var(--max-w);
  margin: 0 auto;
  display: flex;
  justify-content: space-between;
  align-items: start;
  flex-wrap: wrap;
  gap: var(--space-md);
}

.footer-logo {
  font-family: var(--font-display);
  font-weight: 500;
  font-size: 1rem;
  color: var(--navy);
}

.footer-brand p {
  font-size: 0.8rem;
  color: var(--gray-400);
  margin-top: 0.4rem;
  line-height: 1.55;
}

.footer-links {
  display: flex;
  gap: var(--space-md);
}

.footer-links a {
  font-size: 0.82rem;
  color: var(--gray-600);
  transition: color 0.2s;
}

.footer-links a:hover {
  color: var(--navy);
}

.footer-legal {
  width: 100%;
  font-size: 0.72rem;
  color: var(--gray-400);
  margin-top: var(--space-sm);
  padding-top: var(--space-sm);
  border-top: 1px solid var(--gray-200);
}

/* ---- SCROLL REVEAL ---- */

.reveal {
  opacity: 0;
  transform: translateY(20px);
  transition: opacity 0.6s ease, transform 0.6s ease;
}

.reveal.visible {
  opacity: 1;
  transform: translateY(0);
}

/* ---- FOCUS STYLES ---- */

:focus-visible {
  outline: 2px solid var(--blue-primary);
  outline-offset: 2px;
}

/* ---- REDUCED MOTION ---- */

@media (prefers-reduced-motion: reduce) {
  *, *::before, *::after {
    animation-duration: 0.01ms !important;
    transition-duration: 0.01ms !important;
  }
  html { scroll-behavior: auto; }
  .reveal {
    opacity: 1;
    transform: none;
  }
}

/* ---- RESPONSIVE ---- */

@media (max-width: 900px) {
  .hero {
    grid-template-columns: 1fr;
    min-height: auto;
    padding-top: calc(60px + var(--space-lg));
  }

  .hero-genome {
    order: -1;
  }

  .stats-bar {
    grid-template-columns: repeat(2, 1fr);
  }

  .research-grid {
    grid-template-columns: 1fr;
  }

  .team-grid {
    grid-template-columns: repeat(2, 1fr);
  }
}

@media (max-width: 640px) {
  :root {
    --space-xl: 3rem;
    --space-2xl: 4.5rem;
  }

  .nav-links {
    display: none;
    position: fixed;
    top: 60px;
    left: 0;
    right: 0;
    background: var(--navy);
    flex-direction: column;
    padding: var(--space-md);
    gap: var(--space-sm);
    border-bottom: 1px solid rgba(255, 255, 255, 0.08);
  }

  .nav-links.open {
    display: flex;
  }

  .nav-toggle {
    display: block;
  }

  .nav-toggle[aria-expanded="true"] span:first-child {
    transform: rotate(45deg) translate(4px, 4px);
  }

  .nav-toggle[aria-expanded="true"] span:last-child {
    transform: rotate(-45deg) translate(4px, -4px);
  }

  .stats-bar {
    grid-template-columns: 1fr 1fr;
  }

  .stat {
    padding: var(--space-md) var(--space-sm);
  }

  .stat-value {
    font-size: 1.6rem;
  }

  .team-grid {
    grid-template-columns: 1fr;
  }

  .pub {
    grid-template-columns: 1fr;
    gap: var(--space-xs);
  }

  .pub-year {
    order: -1;
  }

  .pub-tag {
    width: fit-content;
  }

  .join-details {
    flex-direction: column;
    gap: var(--space-sm);
  }

  .genome-annotation {
    display: none;
  }

  .footer-inner {
    flex-direction: column;
  }
}